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It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition. Medications This Week's Feature Conductive Keratoplasty Can Improve Farsightedness Conductive keratoplasty is an FDA-approved procedure to treat hyperopia, or farsightedness. Learn more about how this procedure corrects vision by changing the shape of the cornea and what science has to say about the results. Also Inside Visit our library of articles on the following topics: All topics Cancer treatment Common medications Diabetes treatment Heart treatment Prevention Questions and tips Treatment: by condition Treatment: by medication and devices Therapeutic and Wellness Centers Aging and Health Center Alternative Health Center Disease Management Center Healthcare Center	OVARIAN CANCER "THE SILENT KILLER" IN MEMORY OF ALYCE MARIE SIGURDSON DEDICATED TO HER LOVING FAMILY Each year more than 25,000 women are diagnosed with ovarian cancer. Of these, more than 14,000 will die. The lifetime risk of ovarian cancer in women with no family history of the disease is approximately one in 70 (1.4%). Some studies, however, show that it may be as low as one in 55 (1.8%). Because there are rarely any symptoms during the early stages of ovarian cancer, victims don't even know they have it. Once symptoms do appear, the cancer has progressed so far that one's chance of survival is dramatically reduced. Ovarian cancer is the fifth most common cancer and fifth most common cause of cancer death among women. Over half the cases of ovarian cancer in the United States are detected in women over the age of 65, and most are diagnosed at 60. However, every women is at risk. Ovarian cancer has a very high mortality rate, because it often goes undetected until it is quite advanced. WHAT YOU SHOULD DO Have your physician perform a transvaginal ultrasound and a CA-125-II test at least once every year. Early detection is the key to your survival. Being proactive can very well mean the difference between life and death. EARLY DETECTION OF OVARIAN CANCER www.ovariandetection.org WHAT IS OVARIAN CANCER: www.healthandage.com WHAT ARE THE RISK FACTORS OF OVARIAN CANCER -Age The incidence of this cancer rises with age. The American cancer society recommends an annual pelvic exam for all women over the age of forty (40), in hopes it may increase early detection -Birth Control Pills Taking birth control pills appears to reduce the risk of developing ovarian cancer. Additionally the longer they are taken the lower the risk, but the risk of breast cancer is higher while on the pill. -Diet Eating a diet high in fat, especially animal fats has been shown to increase the risk of ovarian cancer. It is higher in western, affluent countries where high fat diets are eaten. -Ethnicity White women in Europe and North America have a higher incidence of ovarian cancer, it is lowest in blacks and Asian women in their native countries. -Genetic Background As with most cancers a family history of ovarian cancer increases the risk. Women who inherit a genetic mutation found in the BRCA1 and 2 genes have a 64% risk of inheriting the disease. The mutation can be found in people of many ethnic backgrounds, but is higher in Asheknazi Jews (from eastern and central Europe). -Pregnancy/Reproductive History Women with no children/pregnancies or who had their first pregnancy after the age of 35 are at higher risk of ovarian cancer. It is also more common in women who had an early puberty (before age 12) or late menopause (after 50). Women who have used fertility drugs may also be at higher risk. WHAT IS CA-125? The CA-125 (carbohydrate antigen) is a substance produced by the endometrium, fallopian tubes, and the lining of the abdominal cavity (peritoneum). CA-125 is a used as a tumor marker. Elevated amounts of CA-125 in a woman's blood and body fluids may increase when cancer of the ovaries is present. FAQ ABOUT CA-125 and THE NEW CA-125II www.monitor.net LYSOPHOSPHATIDIC ACID ("LPA") v. CA-125 In 1998, researchers at the Cleveland Clinic were among those suggesting LPA as a potential biomarker for ovarian cancer. They published their findings in the Journal of the American Medical Association, comparing the accuracy of LPA with CA125 in detecting ovarian cancer. In the study, LPA levels from 48 healthy control women, 48 women with ovarian cancer, 36 women with other gynecologic cancers, 17 women with benign gynecologic diseases, 11 women with breast cancer and 5 women with leukemias were tested for levels of LPA and CA125. Elevated plasma LPA levels were detected in: nine of 10 patients with stage I ovarian cancer; 24 of 24 patients with stage II, III, and IV ovarian cancer; and 14 of 14 patients with recurrent ovarian cancer. Women in the ovarian cancer groups had significantly higher plasma LPA levels than women in the healthy control group. LPA was also useful in detecting 33 of 36 other types of gynecologic cancers. The researchers stressed that these data, however encouraging, were preliminary and ongoing studies will determine the future use of LPA in detecting ovarian cancer. FURTHER INFORMATION ON OVARIAN CANCER www.nlm.nih.gov cancer.gov www.cancercare.org www.csudh.edu www.slip.net www.cancerlinksusa.com www.ovca.org www.reutershealth.com www.cancersource.com www.umm.edu ovariancancer.jhmi.edu members.shaw.ca www.paraplatin.com Pre-Pregnancy Planning Discusses the importance of Folic Acid, Pre-pregnancy check-ups and disease screenings, all of which are vital to your newborn's health. Prenatal Care www.nlm.nih.gov Cytomegalovirus (CMV) and Pregnancy CMV Antibody test should be done in the early stage of pregnancy www.modimes.org Dangerous Drugs for Unborn Babies During Pregnancy AVOID the following: Accutane & Other Retinoids www.marchofdimes.com Cocaine www.marchofdimes.com Alcohol www.marchofdimes.com Smoking www.marchofdimes.com
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